Department of Paraclinical Sciences, University of Pretoria
+27828405194
info@myolab.co.za

Publications

Exercise induced pathophysiology


Hohl R, Blackhurst DM, Donaldson B, Van Boom KM, Kohn TA. Antioxidant enzyme activities do not correlate with muscle fiber type or oxidative metabolism in skeletal muscle from free-roaming wild antelopes. In preparation. 

Breed D, Meyer LCR, Steyl JCA, Goddard A, Burroughs R, Kohn TA. The biological consequences of malignant capture stress – capture myopathy. (2019) Conservation Physiology. 7(1): 559


Muscle weakness in acquired and congenital myopathies


Henning F, Cunninghame CA, Martín MA, Rubio JC, Arenas J, Lucia A, Hernández-Laín A, Kohn TA. Muscle fiber type proportion and size is not altered in McArdle disease. (2017) Muscle & Nerve, 83(Pt 6), 322-323.

Kohn TA, Noakes TD, Rae DE, Rubio JC, Santalla A, Nogales-Gadea G, Andreu AL, Martín MA, Lucia A. McArdle disease does not affect skeletal muscle fibre type profiles in humans. (2014) Biology OPEN. 3(12): 1224-1227.


Nature vs. Nurture


Dada S, Henning F, Kohn TA. Baboon (Papio ursinus) single fibre contractile properties are similar to that of trained humans. (2018) Journal of Muscle Research and Cell Motility. 39(5): 189-199.

Rae DE, Chin T, Dikgomo K, Hill L, McKune AJ, Kohn TA, Roden LC. One night of partial sleep deprivation impairs recovery from a single exercise training session. (2017) European Journal of Applied Physiology. 254(1), 6-14.

Santos-Concejero J, Tucker R, Myburgh KH, Essén-Gustavsson B, Kohn TA. Greater performance impairment of black runners than white runners when running in hypoxia. (2014) International Journal of Sports Medicine. 35(10), 809-816.

Kohn TA. Insights into the skeletal muscle characteristics of three southern African antelope species. (2014) Biology OPEN. 3(11), 1037-1044.

Kohn TA, Noakes TD. Lion (Panthera leo) and caracal (Caracal caracal) type IIx single muscle fibre force and power exceed that of trained humans. Journal of Experimental Biology. (2013), 216, 960-969.

Curry JW, Hohl R, Noakes TD, Kohn TA. High oxidative capacity and type IIx fibre content in springbok and fallow deer skeletal muscle suggest fast sprinters with a resistance to fatigue. (2012) Journal of Experimental Biology, 215, 3997-4005.

Kohn TA, Curry JW, Noakes TD. Black wildebeest skeletal muscle exhibits high oxidative capacity and a high proportion of type IIx fibres. (2011) Journal of Experimental Biology, 214, 4041-4047.

Kohn TA, Essén-Gustavsson B, and Myburgh KH. Specific muscle adaptations in type II fibres after high intensity interval training of well-trained runners. (2011) Scandinavian Journal of Medicine and Science in Sports, 21, 765–772.

Kohn TA, Burroughs R, Hartman MJ, Noakes TD. Fiber type and metabolic characteristics of lion (Panthera leo), caracal (Caracal caracal) and human skeletal muscle. (2011) Comparative Biochemistry and Physiology A, 159(2), 125-133.

Harley XYR, Kohn TA, Gibson A, Noakes TD and Collins M. Skeletal muscle monocarboxylate transporter content is not different between black and white runners. (2009) European Journal of Applied Physiology, 105(4), 623-632.

Kohn TA, Hoffman LC, and Myburgh KH. Identification of myosin heavy chain isoforms in skeletal muscle of four Southern African wild ruminants. (2007) Comparative Biochemistry and Physiology A, 148(2), 399-407.

Kohn TA, Essén-Gustavsson B, and Myburgh KH. Exercise pattern influences skeletal muscle hybrid fibers of runners and non-runners. (2007) Medicine and Science in Sports and Exercise, 39(11), 1977-1984.

Kohn TA, Essén-Gustavsson B, and Myburgh KH. Do skeletal muscle phenotypic characteristics of Xhosa and Caucasian endurance runners differ when matched for training and racing distances? (2007) Journal of Applied Physiology, 103, 932-940.

Kohn TA, Kritzinger B, Hoffman LC, and Myburgh KH. Characteristics of impala (Aepyceros melampus) skeletal muscles. (2005) Meat Science, 69, 277-282.


Obesity & Type II diabetes


Webster CC, Noakes TD, Chacko SK, Swart J, Kohn TA, Smith JAH. Gluconeogenesis during endurance exercise in cyclists habituated to a long-term low carbohydrate high fat diet. (2016) Journal of Physiology, 594(15), 4389-4405.

Goyaram V, Kohn TA, Ojuka EO. Suppression of the GLUT4 adaptive response to exercise in fructose-fed rats. (2014) American Journal of Physiology. 306(3), E275-E283.

Smith JAH, Kohn TA, Chetty AK, Ojuka EO. CaMK activation during exercise is required for histone hyper-acetylation and MEF2A binding at the MEF2 site on the Glut4 gene. (2008) American Journal of Physiology, 295(3), E698-E704.

Mukwevho E, Lang D, Kohn TA, Nyatia E, Smith J, Ojuka E. Caffeine induces hyperacetylation of histones at the MEF2 site on the GLUT4 promotor and increases MEF2A binding to the site via a CaMK-dependent mechanism. (2008) American Journal of Physiology, 294, E582-588.


Techniques


Smith JAH, McKerrow AD, Kohn TA. Metabolic cost of running differs between two types of laboratory treadmills. (2017) Journal of Sports Sciences. 35(16), 1592-1597.

Kohn TA, Myburgh KH. Regional specialisation of rat quadriceps myosin heavy chain isoforms occurring in distal to proximal parts of middle and deep regions is not mirrored by citrate synthase activity. (2007) Journal of Anatomy, 210(1), 8-18.

Kohn TA, Myburgh KH. Electrophoretic separation of human skeletal muscle myosin heavy chain isoforms: importance of reducing agents. (2006) Journal of Physiological Sciences, 56(5), 355-360.